PENGARUH VARIASI KONSENTRASI KARBOPOL 940 TERHADAP MUTU FISIK SEDIAAN EMULGEL EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) SEBAGAI TABIR SURYA SECARA In Vitro

Authors

  • Ayunda Syifa Widitasari Setia Budi University
  • Endang Sri Rejeki
  • Nur Aini Dewi Purnamasari

DOI:

https://doi.org/10.26418/edunaturalia.v4i2.69346

Abstract

Secondary metabolite like phenolic compounds found in kersen leaves have function to bind free radical. Emulgel is a preparation that is not greasy, spreads evenly, soft, and long lasting on storage. The objective of this study was to determine the physical quality of emulgel of kersen leave ethanol extract with various concentrations of carbopol 940, to determine the potential and effective concentration of carbopol 940 in emulgel of kersen leave ethanol extract as a sunscreen. This study used several formula with various concentration of carbopol 940 which is 1, 1.5, and 2%. Physical quality testing include organoleptic, homogeneity, spreading power test, adhesion test, pH test, and viscosity test. Determination of Sun Protecting Factor (SPF) value was carried out in vitro using UV-Vis spectrophotometry and Mansyur Calculation. The results obtained showed that emulgel of kersen leave ethanol extract with variations of the gelling agent carbopol 940 was stable for 21 days on storage and have activity as a sunscreen. Emulgel of kersen leave ethanol extract (Muntingia calabura L.) 1% concentration of carbopol 940 is the most effective as a sunscreen preparation with 25,42 SPF value which categories ultra protection.

Keywords: kersen leave ethanol estrak, emulgel, sunscreen, SPF.

Author Biography

Ayunda Syifa Widitasari, Setia Budi University

Lulusan Universitas Setia Budi Fakultas Farmas Prodi S1 Farmasi tahun 2023 menyandang gelar Cumlaude dengan IPK 3.88

References

Lestari, Susi Merdi. (2019). Formulasi dan Pengujian Sun Protecting Factor (SPF) Emulgel Fraksi Etil Asetat Daun Sirih Merah (Piper crocatum Ruiz dan Pav) Sebagai Tabir Surya Secara In Vitro. Skripsi. Universitas Setia Budi, Surakarta.

Irianningrum, R. (2019). Formulasi Dan Uji AKtivitas Perlindungan Tabir Surya Gel Ekstrak Etanol Daun Kemangi (Ocimum americanum L.) Secara In Vivo dan In Vitro. Universitas Setia Budi.

Mintorini, E., Fitriana, S., & Astuti, M. D. (2013). Struktur anatomi dan uji aktivitas antioksidan ekstrak metanol daun kersen (Muntingia calabura). Prosiding SEMIRATA, 1(1).

Mulangsri, D. A. K., dan Puspitasari, A. D. (2018). Uji Aktivitas Tabir Surya Ekstrak Etanol Daun Kersen (Muntingia calabura). Cendekia Eksakta, 2(2).

Anggreany, R. T., Rahmawati, I., & Leviana, F. (2020). Uji Antibakteri Ekstrak dan Fraksi Herba Ceplukan (Physalis angulata L.) Untuk Mengatasi Infeksi Staphylococcus epidermidis Selama Perslinan. Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan, 11(1): 253-263.

[Kemenkes RI] Kementerian Kesehatan Republik Indonesia. (2017). Farmakope Herbal Indonesia Edisi II.

Dominica, D. danHandayani, D. (2019). Formulasi dan Evaluasi Sediaan Lotion dari Ekstrak Daun Lengkeng (Dimocarpus Longan) sebagai Antioksidan. Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 6(1): 1–7.

Mansur J. Determinação do fator de proteção solar por espectrofotometria. An. Bras. Dermantol. 1986;61:121-124.

Octavia, N. (2016). Formulasi Sediaan Gel Hand Sanitizer Minyak Atsiri Pala (Myristica fragransHoutt.) Uji Stabilitas Fisik Dan Uji Aktivitas Antibakteri Terhadap Bakteri Staphylococcus aureus. Skripsi. Fakultas Farmasi Universitas Muhammadiyah Surakarta

Andriani, V. H. 2018. Optimasi Emulgel Zinc Oxide Nanopartikel dengan Carbopol 940 Sebagai Gelling Agent dan Propilen Glikol Sebagai Humektan dan Uji Aktivitas Tabir Surya Secara In Vitro. Skripsi. Fakultas Farmasi Universitas Muhammadiyah Surakarta.

Priani, S. E., Permana, R. A., Nurseha, M., Aryani., R. 2021. Pengembangan Sediaan Emulgel Antioksidan dan Tabir Surya Mengandung Ekstrak Kulit Buah Cokelat (Theobroma cacao L). Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 8(3): 264-270.

Anggraini, S. N. 2019. Pengaruh Konsentrasi Carbopol 940 PadaSediaan Emulgel Ekstrak Etanol Daun Bandotan (Ageratum conyzoides L.) Terhadap Sifat Fisik Dan Penyembuhan Infeksi Staphylococcus aureus ATCC 25923 Pada Kelinci. Skripsi. Fakultas Farmasi. Universitas Setia Budi Surakarta.

Supomo, Sapri, Astri NK. 2016. Formulasi Gel Antioksidan Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.) Dengan Basis Carbopol. Jurnal Ilmiah Ibnu Sina, 1(1): 50-60.

Widyawati, E. Ayuningtyas, N. D., Pilatirisa, A. P. 2019. Penentuan Nilai SPF Ekstrak dan Losio Tabir Surya Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Dengan Metode Spektrofotometri UV-Vis. Jurnal Riset Kefarmasian Indonesia, 1 (3): 189-202.

[FDA] Food and Drug Administration. 2017. Cosmetics science and research. https://www.fda.gov/cosmetics/cosmetics-science-research

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Published

2023-11-29

Issue

Vol. 4 No. 2 (2023)

Section

Articles

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