MOLECULAR DOCKING AND ADME STUDIES OF STIGMASTEROL COMPOUNDS AS ANTI-BREAST CANCER
DOI:
https://doi.org/10.26418/indonesian.v8i1.83224Abstract
Molecular docking studies of stigmasterol (test ligand) and estradiol (control ligand) against the ER-α receptor were performed using PyRx software. This study aims to determine the interaction between stigmasterol ligands and ER-α receptors by the molecular docking method using PyRx. The study results show that stigmasterol and estradiol have the same binding energy value of -7.3 kcal/mol. The stigmasterol compound could therefore be used as a candidate for breast cancer drugs.References
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