UJI AKTIVITAS EKSTRAK ETANOL DAUN SINGKONG (Manihot utilissima Pohl) SEBAGAI LARVASIDA Aedes aegypti

Abstract

Background. Dengue Haemorrhagic Fever is a very dangerous virus
disease because it can cause people die quickly (a few days). One of the
efforts to overcome the disease is using larvacide. Cassava"™s leaves
(Manihot utilissima Pohl) contain saponins and flavonoids that have
larvacide activity. Objective. The purpose of this research is to know the
activity of cassava"™s leaves ethanol extract as larvacide of Aedes aegypti,
to know the compounds that contained in cassava"™s leaves, to determine
concentration of cassava"™s leaves ethanol extract which has larvacide
activity with LC
and to analyze larvacide activity comparison between
cassava"™s leaves ethanol extract and temephos. Methodology. 1125
instar III/IV Aedes aegypti larvae were used for this experiment which
divided into nine groups. The groups were one negative control group
(aquades), one positif control group (temephos) and seven experimental
groups with concentration of 0,5%, 1%, 1,5%, 2%, 2,5%, 3% and 3,5%.
Each group consist of 25 larvae. Each experiment was replicated five
times. Mortality rate data was analyzed with One Way Anova Test and
then continued with Tukey Test. Probit Analysis was used to know the
value of LC
90
90,
. Results. Cassava"™s leaves ethanol extract has larvacide
activity to Aedes aegypti with LC
value at 2,613%. There is no
significance difference of larvacide activity between cassava"™s leaves
ethanol extract with concentration of 3% and 3,5% compared to temephos.
Conclusion. Cassava"™s leaves ethanol extract has larvacide activity to
Aedes aegypti.
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Keywords: Ethanol extract, cassava"™s leaves, larvacide, Aedes aegypti
1)Medical School, Faculty of Medicine, University of Tanjungpura,
Pontianak, West Borneo
2)Pharmacy School, Faculty of Medicine, University of Tanjungpura,
Pontianak, West Borneo
3)Departement of Parasitology, Medical School, Faculty of Medicine,
University of Tanjungpura, Pontianak, West Borneo