UJI AMILUM BATANG KELAPA SAWIT (Elaeis guineensis Jacq.) SEBAGAI BAHAN PENGISI PADA TABLET KLORFENIRAMIN MALEAT (CTM) DENGAN METODE GRANULASI BASAH

Abstract

The waste from palm’s trunk was consist of starch which expected can be used as tablet filler material. This research was to test the palm’s trunk starch aschlorpheniramine maleat (CTM) tablet filler material and to test its’ physics. Tablet fillermaterial in comparation formulae was using the lactose (K1) and the test tablet formulaewas using the palm’s trunk starch (K2). The tablet was made by the wet granulationmethod. The physics test’s result of both formula showed that the tablet had eligible resultin the uniformity of weight, friability, hardness, disintegration period, assay, contentuniformity, and tablet’s dissolution test. The analysis independent T test result by usingSPSS 17.0 showed that p<0,05 so the both formula was different, except for the contentuniformity and tablet’s dissolution test. The palm’s trunk starch can be used as CTMtablet filler material with the physics characteristic wasn’t as good as the comparationformulae tablet.
Keywords : Palm’s Trunk Starch, Tablet, Filler Material and CTM.