ORMULASI TABLET KUNYAH DARI EKSTRAK ETANOL CABAI RAWIT (Capsicum frutescens L.) DENGAN VARIASI PENGISI MANITOL "“ DEKSTROSA MENGGUNAKAN METODE GRANULASI BASAH

Abstract

Cabai rawit (Capsicum frutescens L.)   is a plant that contain flavonoid and had an
antioxidant activity. Cabai rawit extracts were made as a chewable tablet with purpose to
increase the acceptablet of herb medicine in the society. This research was done to learn the
effect of variation of filler combination mannitol-dextrose. The chewable tablets were made into
three formulas, FI with combination of mannitol-dextrose (80:20%); FII (50:50%); and FIII
(20:80%). The chewable tablet then got physical evaluation such as physical appearance, size
uniformity, weight uniformity,   hardness, friability, disintegration time and taste response test.
The results of the evaluation was the variation of filler combination affect the hardness of tablet,
friability, desintegration and the taste of tablet. The best result of physical evaluation of
chewable was FII with combination of mannitol-dextrose (50:50%).
Keywords : Cabai rawit, mannitol, dextrose, chewable tablet, wet granulation