UJI EFEKTIVITAS ANTIOKSIDAN KRIM EKSTRAK ETANOL BIJI PEPAYA (Carica papaya L.) TERHADAP DPPH (1,1-diphenyl-2-picrylhydrazil)

Abstract

Seeds of papaya (Carica papaya L.) is a part of plant that potentially as a natural
antioxidant. This study aims to determine the IC50 values, physical and chemical properties
and antioxidant activity of ethanol extract of papaya seeds cream compared with positive
control. This research was conducted by the DPPH (1,1-diphenyl-2-picrilhydrazil) method
by spectrophotometric at λ max 516.0 nm. Cream consists of 5 formulas with various
concentrations of the extract FI 0.8%, 1.6% F II, F III 2.4%, 3.2% F IV and FV 4%. The
results showed that the ethanol extract all the cream papaya seeds have greater antioxidant
activity than the positive control. F II had the highest activity at 94.228% with IC50 value
of 867.68 µg/ml. PH and particle size of all cream is good, but the cream F III, F IV and F
V had creaming. F II scent most favored, while the color, consistency and sensation of the
skin which is most preferred to the F I. Based on the phytochemical screening, ethanol
extract of papaya seeds contain phenols, flavonoids, alkaloids and vitamin C.

Keywords: Ethanol Extract of Papaya Seed, Antioxidants, DPPH.