This research aims to know the effect of the science process skill approach with video-based learning of human digestive system learning material for grade VIII, Pontianak state 5 Junior High School. The form of this research is the quasi-experimental design with a nonequivalent control group design. The sampling technique uses the intac group, grade VIII A as the experimental class and grade VIII B as the controller class. The research instrument is multiple choice with 20 questions. The average of the experimental class test result is 14.70 higher than the controller class 13.20 with 20 as the maximum score. Based on U Mann"“Whitney test, it shows that the Zcount (-2.22) < -Ztable (-1,96), which means there is significant difference between the use of science skill with the video-based learning approach than the conventional approach. The effect size score is 0.53 which can be categorized as the highest category and give a big impact in 20.10%.
