AKTIVITAS EKSTRAK METANOL RIMPANG LENGKUAS MERAH (Alpinia purpurata K. Schum) TERHADAP PERTUMBUHAN JAMUR Malassezia furfur

Abstract

Malassezia furfur is a fungal that causes tinea versicolor which attacks the stratum corneum in the epidermis of the skin. Red galangal rhizome (Alpinia purpurata K. Schum) is a plant that has various properties including antifungals. This research aims to find out the effect of methanol extract from red galangal rhizome (A. purpurata) against the growth of the fungus M. furfur and to know the concentration of methanol extract from red galangal rhizome (A. purpurata) which is included in the category of strong inhibition to inhibit the growth of the fungus M. furfur. This research used the paper disc diffusion method, carried out with 6 levels of treatments consisting of negative control (DMSO 10%), positive control (ketoconazole), and 4 different concentrations of red galangal rhizome (A. purpurata), which were 0.25; 0.50; 0.75; and 1.00 g/mL. The results showed that the red galangal rhizome extract provided antifungal activity against the test fungus which was indicated by the presence of an inhibition zone produced. The concentration of 1.00 g/mL showed results that were included in the category of strong inhibition on the growth of M. furfur with an average yield of 11.98 mm at 48 hours incubation period. The concentration of 0.25 g/mL showed the smallest inhibition with an average yield of 7.85 mm at the same incubation period.