Potential of Cashew Leaves (Anacardium occidentale L) for Health

Authors

  • Willy Wijayanti Department of Food Technology, State Polytechnic of Sriwijaya
  • Abraham Horisanto Department of Food Technology, State Polytechnic of Sriwijaya
  • Ilham Wahyu Pamungkas Department of Food Technology, State Polytechnic of Sriwijaya
  • Syerina Raihatul Jannah Department of Food Technology, State Polytechnic of Sriwijaya
  • Venny Agustin Department of Food Technology, State Polytechnic of Sriwijaya

DOI:

https://doi.org/10.26418/jft.v7i2.90385

Keywords:

Anacardium occidentale, bioactive compound, cashew leaf

Abstract

Traditionally employed in folk medicine, cashew leaf (Anacardium occidentale L.) has recently attracted a lot of scientific attention because of its possible health advantages. According to recent research, cashew leaves are abundant in bioactive substances such as terpenoids, flavonoids, and tannins that have a variety of pharmacological actions, such as anti-inflammatory, anti-cancer, antidiabetic, and antioxidant qualities. These bioactive chemicals work through a variety of molecular processes, including scavenging free radicals, modifying inflammatory pathways, and increasing the activity of antioxidant enzymes. Studies conducted both in vitro and in vivo have demonstrated the potential of cashew leaf extracts in the treatment of a number of chronic illnesses, such as diabetes mellitus and other degenerative conditions. Additionally, cashew leaves have encouraging opportunities as a natural source for the creation of medications and functional foods, including herbal remedies, dietary supplements, and natural cosmetics. More research is needed to find out if cashew leaf extracts are safe and effective over the long term and to figure out exactly how these bioactive chemicals work. In order to maximize the use of cashew leaves, future research should concentrate on identifying the main bioactive chemicals, improving extraction techniques, and creating appropriate formulations.

References

Agustin Yeni. Uji in vitro ekstrak etanol daun jambu mete (Anacardium occidentale, L) sebagai antibakteri terhadap bakteri Staphylococcus aureus. J Ilmiah Bakti Farmasi. 2023;8(1):41-46.

Ajileye OO, Obuotor EM, Akinkunmi EO, Aderogba MA. Isolation and characterization of antioxidant and antimicrobial compounds from Anacardium occidentale L. (Anacardiaceae) leaf extract. J King Saud Univ Sci. 2015;27:244-252.

Akinpelu DA. Antimicrobial activity of Anacardium occidentale bark. Fitoterapia. 2001;72(3):286-287.

Andarwulan N, Kurniasih D, Apriady RA, Rahmat H, Rotoc AV, Bolling BW. Polyphenols, carotenoids, and ascorbic acid in underutilized medicinal vegetables. J Funct Foods. 2012;4(1):339-347.

Ariyani M, Kusumaningsih T, Rahardjo MB. Daya hambat ekstrak daun jambu mete (Anacardium occidentale Linn) terhadap pertumbuhan Streptococcus sanguis. Jurnal PDGI. 2007;57:45-51.

Awakan OJ, Malomo SO, Adejare AA, Igunnu A, Atolani O, Adebayo AH, Owoyele BV. Anti-inflammatory and bronchodilatory constituents of leaf extracts of Anacardium occidentale L. in animal models. J Integr Med. 2018;16(1):62-70.

Baptista A, Goncalves RV, Bressan J, Peluzio M. Antioxidant and antimicrobial activities of crude extracts and fractions of cashew (Anacardium occidentale L.), cajui (Anacardium microcarpum), and pequi (Caryocar brasiliense C.): A systematic review. Oxid Med Cell Longev. 2018:1-13.

BPS. Produk Domestik Bruto Indonesia Triwulanan tahun 2022-2024. Badan Pusat Statistik;.

Chabi S, Adoukonou-Sagbadja H, Ahoton L, Adebo I, Adigoun F, Saidou A, et al. Indigenous knowledge and traditional management of cashew (Anacardium occidentale L.) genetic resources in Benin. JEBAS. 2013;1:375-382.

Chan EWC, Kong LQ, Yee KY, Chua WY, Loo TY. Rosemary and sage outperformed six other culinary herbs in antioxidant and antibacterial properties. Int J Biotechnol Wellness Indust. 2012;1(2):142-151.

Chan EWC, Kong LQ, Yee KY, Chua WY, Loo TY. Antioxidant and antibacterial properties of some fresh and dried Labiatae herbs. Free Radical Antioxid. 2012;2(3):20-27.

Chan EWC, Tan YP, Chin SC, Gan LY, Kang KX, Fong CH, Chang HQ, How YC. Antioxidant properties of selected fresh and processed herbs and vegetables. Free Radical Antioxid. 2014;4(1):39-46.

Chan EWC, Baba S, Chan HT, Kainuma M, Inoue T, Wong SK. Ulam herbs: A review on the medicinal properties of Anacardium occidentale and Barringtonia racemosa. J Appl Pharm Sci. 2017;7:241-247.

da Silva RA, Liberio SA, do Amaral FM, do Nascimento FRF, Torres LMB, Neto VM, Guerra RNM. Antimicrobial and antioxidant activity of Anacardium occidentale L. flowers in comparison to bark and leaves extracts. J Biosci Med. 2016;4:1-9

Dare SS, Hamman WO, Musa S, Goji ADT, Oyewale AA, Abba S, Ezekiel I. Effects of aqueous extract of Anacardium occidentale (cashew) leaf on pregnancy outcome of Wistar rats. Int J Anim Vet Adv. 2011;3(2):77-82.

Dinas Perkebunan Dati I Irian Jaya. Lembar Informasi Pertanian (LIPTAN) LPTP Koya Barat: Pemupukan Tanaman Jambu Mete. Jayapura: Loka Pengkajian Teknologi Pertanian Koya Barat; 1997.

Direktorat Tanaman Semusim dan Tahunan. Laporan Kinerja Direktorat Tanaman Semusim dan Tahunan Tahun 2023. Jakarta: Direktorat Tanaman Semusim dan Tahunan; 2023.

Encarnação S, de Mello-Sampayo C, Graça NAG, Catarino L, da Silva IBM, Lima BS, Silva OMD. Total phenolic content, antioxidant activity and pre-clinical safety evaluation of an Anacardium occidentale stem bark Portuguese hypoglycemic traditional herbal preparation. Ind Crops Prod. 2016;82:171-178.

Halid N, Nurhatidjah, Saleh A. Uji stabilitas fisik ekstrak etanol daun jambu mete (Anacardium occidentale L.) dalam formulasi sediaan emulgel anti-inflamasi. Jurnal Mandala Pharmacon Indonesia. 2019;5:48-55.

Hutabarat MRT, Hanifah FN, Hadijah S, Winarso D, Murwani S. Pemberian ekstrak etanol daun jambu mete dalam reduksi kadar IL-6 dan peningkatan kadar SOD pada mencit fibrosis hepar yang diinduksi CCl4. Jurnal Sain Veteriner. 2020;38:12-19.

Ikyembe D, Pwavodi C, Agbon AN. Hepatoprotective effect of methanolic leaf extract of Anacardium occidentale (cashew) on carbon tetrachloride-induced liver toxicity in Wistar rats. Sub-Saharan Afr J Med. 2014;1(3):124.

Jaiswal YS, Tatke PA, Gabhe SY, Vaidya AB. Antidiabetic activity of extracts of Anacardium occidentale Linn. leaves on n-streptozotocin diabetic rats. J Tradit Complement Med. 2017;7(4):421-427.

Konan NA, Bacchi EM. Antiulcerogenic effect and acute toxicity of hydro-ethanolic extract from the cashew (Anacardium occidentale L.) leaves. J Ethnopharmacol. 2007;112:237-242.

Kongkachuichai R, Charoensiri R, Yakoh K, Kringkasemsee A, Insung P. Nutrients value and antioxidant content of indigenous vegetables from Southern Thailand. Food Chem. 2015;173:838-846.

Karmawati E. Perkembangan Jambu Mete dan Strategi Pengendalian Hama Utamanya. Perspektif. 2008;7(2):102-111.

Maryanti D. Pemanfaatan buah jambu monyet sebagai obat herbal alternatif untuk menunjang kesehatan dalam bentuk kapsul jambu monyet (JAMET). Inisiasi. 2022;11(1):67-74.

Mawaddah, Setiawan H, Saragih H. 2020. Aktivitas ekstrak etanolik daun jambu mete terhadap otot pectoralis thoracicus ayam jawa super. Indonesian J Anim Sci. 2020;22:80-88. doi: 10.25077/jpi.22.1.80-88.2020.

Mukhlis, Maruka SS, Nurfadilah. Pengaruh penambahan ekstrak daun jambu mete terhadap total bakteri dan mutu sensori permen herbal rumput laut. Buletin Poltanesa. 2022;23:871-876.

Nonci FY, Rusdi M, Mohan L. Uji toksisitas akut ekstrak etanol klika jambu mede (Anacardium occidentale, L) pada mencit jantan (Mus musculus). JF FIK UINAM. 2014;2(2):62-68.

Olaniyan MF. Lowering effect of cashew leaf (Anacardium occidentale) extract on egg yolk induced hypercholesterolaemic rabbits. Sch Acad J Biosci. 2016;4(10B):886-891.

Putri MA. Peningkatan antioksidan endogen yang dipicu latihan fisik. YARSI Med J. 2018;26(3):163-172.

Razali N, Razab R, Junit SM, Aziz AA. Radical scavenging and reducing properties of extracts of cashew shoots (Anacardium occidentale L.). J Food Chem. 2008;111:38-44.

Reihani SFS, Azhar ME. Antioxidant activity and total phenolic content in aqueous extracts of selected traditional Malay salads (Ulam). Int Food Res J. 2012;19:1439-1444.

Salehi B, Gültekin-Özgüven M, Kirkin C, Özçelik B, Morais-Braga MFB, Carneiro JNP, Bezerra CF, da Silva TG, Coutinho HDM, Amina B, Armstrong L, Selamoglu Z, Sevindik M, Yousaf Z, Sharifi-Rad J, Muddathir AM, Devkota HP, Martorell M, Jugran AK, Cho WC, Martins N. Antioxidant, antimicrobial, and anticancer effects of Anacardium plants: An ethnopharmacological perspective. Front Endocrinol. 2020;11:295.

Sambo M, Lembo T, Cleaveland S, Ferguson HM, Sikana L, Simon C, Urassa H, Hampson K. Knowledge, attitudes and practices (KAP) about rabies prevention and control: A community survey in Tanzania. PLoS Negl Trop Dis. 2014;8(12):e3410.

Sholihah D, Qomariyah N. Pengaruh ekstrak daun jambu mete terhadap kadar asam urat dan histopatologi ginjal mencit diabetes. LenteraBio: Berkala Ilmiah Biologi. 2021;10(3):356-365.

Shukri MA, Alan C. Analysis of phenolics in Anacardium occidentale shoot extracts using a reversed-phase high performance liquid chromatography tandem mass spectrometry (RPHPLC-MS). J Trop Agric Food Sci. 2010;38(2):221-230.

Sinlapapanya P, Sumpavapol P, Buatong J, Benjakul S. Ethanolic cashew leaf extract: Antioxidant potential and impact on quality changes of dried fermented catfish during storage. Future Foods. 2024;9:100296.

Sulaiman SF, Sajak AAB, Ooi KL, Seow EM. Effect of solvents in extracting polyphenols and antioxidants of selected raw vegetables. J Food Compos Anal. 2011;24:506-515.Sulistyawati D, Mulyati S. Uji aktivitas antijamur infusa daun jambu mete (Anacardium occidentale L.) terhadap Candida albicans. Biomedika. 2009;2:47-51.

Syafaat M, Erwan E, Handoko J. Karakteristik karkas ayam broiler fase finisher yang diberi ekstrak daun jambu mete (Anacardium occidentale Linn.) di dalam air minum: Carcass characteristics in finisher-broiler chickens by supplementation of cashew leaf extract (Anacardium occidentale Linn.) in drinking water. J Livestock Anim Health. 2021;4:63-70

Thangavel K, Kalaichelva P, Arul D. Antioxidant and antimicrobial activity using different extracts of Anacardium occidentale. Int J Appl Biol Pharm Technol. 2011;17(2):436-443.

Tedong L, Dzeufiet PD, Dimo T, Asongalem EA, Sokeng SN, Flejou JF, Callard P, Kamtchouing P. Acute and subchronic toxicity of Anacardium occidentalle Linn (Anacardiaceae) leaves hexane extract in mice. Afr J Trad CAM. 2007;4(2):140-147.

Tan YP, Chan EWC. Antioxidant, antityrosinase and antibacterial properties of fresh and processed leaves of Anacardium occidentale and Piper betle. Food Biosci. 2014;6:17-23.

Thaidi N, Mat Jusoh H, Ghazali AB, Susanti D, Haron N. The effect of bioactive polyphenols from Anacardium occidentale Linn. leaves on α-amylase and dipeptidyl peptidase IV activities. Indonesian J Chem. 2020;20:1010. doi: 10.22146/ijc.44807.

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